Simic Mutants is the obvious home, but the question worth asking is what the deck looks like when Genghis Frog is the signpost rather than curve filler. The Mutagen engine reads as a tempo neutralizer in a format where common combat math sits at 2/2 and 2/3 bodies: a sorcery-speed counter you have to pre-load means you pay mana on turn three to win a turn-four trade, exactly the rate a medium-speed midrange deck can absorb. The trample on the 1/3 is the second pressure relief. Once a Mutagen lands on the Frog, it punches through the wall of 2/3s without contesting the air.
Take it P1P1 to move into GU. Out of color it sits P1P3 to P1P5 as the signpost legend you splash via Escape Tunnel or TCRI Building when your seat is open. The hybrid commons (Mechanized Ninja Cavalry, Putrid Pals) make a Sultai or Bant splash on the Mutant base defensible, and the utility lands keep that mana honest. Maindeck always.
The friction is real, but it isn't the entrance trigger. Stomped by the Foot kills the Frog, yet the enters trigger has already resolved and left a Mutagen behind, so removal is a clean trade rather than a blowout. The sharper punisher is Grounded for Life, which is cheaper against a tapped creature and catches the turn you sacrifice a token. With one Mutant in play and no follow-up, the card is a 1/3 for two with a dead trigger. That floor is what keeps it out of the bomb conversation; the ceiling, which only shows up at four or more Mutants stacking counters onto one threat, wins games on its own.
