Wrap in Vigor

Most green regeneration is a one-shot shield on a single body: the classic regen line guarded one creature at a time, and effects like Vines of Vastwood bundle protection onto one chosen target. This widens that shield to your entire board at instant speed, which reframes when it matters. Regeneration does nothing against bounce, against damage that fails to destroy, or against sacrifice; it earns its keep against exactly one thing, a destruction-based sweeper resolving into a developed green army. Cast it in response to the sweeper so the shields are set, let the sweeper resolve, and every creature you control survives tapped but alive, the most lopsided answer available to a sorcery-speed wrath. The catch is structural: regeneration is a replacement effect, not prevention. It cannot stop exile-based removal, it folds to sweepers that exile rather than destroy, and any board wipe printed with an explicit "creatures can't be regenerated" clause shuts it off entirely, which is why pointing it at the marquee white and black wraths is a trap rather than a plan. Against single-target spot removal it is wildly overpriced for protecting one body. That narrowness keeps it off the green staple list: it answers one category of threat and shrugs at the rest. But against the destruction sweeper it cannot be exiled past, it does work no spot trick can match, at the price of a cantrip, with your board left fully intact.